Gene mutation causes asthma
From Medical News Today:
A team of researchers at Weill Cornell Medical College, Columbia University Medical Center and SUNY Downstate Medical Center have found the cause of a common type of childhood asthma, and it's not rooted in allergens.
The way in which asthma develops is a subject of much scientific interest, considering that the way it develops and affects people varies considerably.
The team identified that an over-active gene "ORMDL3" was linked to around 30 percent of childhood asthma cases. The gene is responsible for disrupting the synthesis of lipid molecules (known as sphingolipids). They aren't fully sure how a reduced production of sphingolipids can cause asthma, yet the results of their study clearly indicate there is a link. Read more.